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ADC Linkers

t-butyl-C18-D-Glu-OtBu-PEG2-amide-PEG2-azide

Catalog: TASK-21-1000175   CAS NO.: N/A
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Description

t-butyl-C18-D-Glu-OtBu-PEG2-amide-PEG2-azide is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and an azide. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. This compound is also an intermedite in the synthesis of semaglutide.

Specifications

CAS No.N/A
FormulaC44H82N6O11
Molecular Weight871.2
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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