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Azide-PEG3-MMAF

Catalog: TASK-21-2000019   CAS NO.: N/A
  • 1mg
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  • 10mg

$68.25$68.25

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Description

Azide-PEG3-MMAF is a synthetic molecule designed for use in the development of antibody-drug conjugates (ADCs). The azide group is a reactive functional group that can participate in bioorthogonal click chemistry reactions, particularly azide-alkyne cycloaddition reactions. PEGylation is often used to improve the pharmacokinetic properties of molecules. MMAF is a potent cytotoxic agent derived from the natural product dolastatin 10. It belongs to the auristatin family and functions as a microtubule inhibitor, disrupting microtubule dynamics in cells. Azide-PEG3-MMAF can be conjugated to monoclonal antibodies or other targeting moieties. The azide group serves as the reactive site for bioorthogonal click chemistry.

Specifications

CAS No.N/A
FormulaC48H80N8O12
Molecular Weight961.2
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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