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PEG Linkers with Small Molecular

N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-acid

Catalog: TASK-18-8000140   CAS NO.: N/A
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$68.25$68.25

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Description

N-(Methyltetrazine-PEG4)-N-Biotin-PEG4-acid is composed of a biotin moiety for specific binding to avidin or streptavidin, PEG spacers for solubility and flexibility, a methyltetrazine group for selective bioconjugation with strained alkenes, and an acidic functional group that may facilitate further conjugation or modification reactions. Methyltetrazine is a reactive group commonly used in bioconjugation chemistry, particularly in inverse-electron-demand Diels-Alder (IEDDA) reactions. Methyltetrazines specifically react with strained alkenes, such as trans-cyclooctenes or transcyclooctynes, to form covalent bonds under physiological conditions. This reaction is highly selective and bioorthogonal, meaning it occurs selectively in biological environments without interfering with native biomolecules.

Specifications

CAS No.N/A
FormulaC42H66N8O13S
Molecular Weight923.1
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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