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ADC Linkers

Mal-PEG1-Val-Cit-PAB-OH

Catalog: TASK-21-1000030   CAS NO.: 2055041-37-5
  • 100mg
  • 250mg

$68.25$68.25

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Description

Mal-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). Maleimide groups are known for reacting specifically with thiol (-SH) groups, such as those present in cysteine residues of proteins. The Val-Cit is specifically cleaved by cathepsin B. PAB-OH is frequently used as a linker to attach other molecules, such as drugs or imaging agents, to a targeting ligand.

Specifications

CAS No.2055041-37-5
FormulaC27H38N6O8
Molecular Weight574.6
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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