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ADC Linkers

Mal-Amido-PEG8-Val-Cit-PAB-OH

Catalog: TASK-21-1000038   CAS NO.: 2387738-43-2
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$68.25$68.25

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Description

Mal-Amido-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). Maleimide groups are known for reacting specifically with thiol (-SH) groups, such as those present in cysteine residues of proteins. Amide bonds are commonly used for linking different molecules together, and they are found in various bioconjugation strategies. The Val-Cit is specifically cleaved by cathepsin B. PAB-OH is used as a linker to attach other molecules, such as drugs or imaging agents, to a targeting ligand.

Specifications

CAS No.2387738-43-2
FormulaC44H71N7O16
Molecular Weight954.1
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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