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Biotinylation Reagents

DOTA-Biotin-Sarcosine | CAS 180978-54-5

Catalog: TASK-36-1000114   CAS NO.: 180978-54-5
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Description

DOTA-Biotin-Sarcosine or (N-methyl-N-(hexahydro-2-oxo-1H-thieno[3,4-d]-imidazol-4-yl)-oxopentyl)glycyl-2-(S)-(4-aminobenzyl)-1,4,7,10-tetraacetic acid-1,4,7,10-tetraazacyclododecane is a valuable tool in biomedical imaging and therapy to biotechnological research and diagnostics due to its ability to combine chelation (DOTA), biotin-streptavidin interaction, and molecular targeting (via sarcosine). DOTA is a chelating agent known for its ability to complex with metal ions, particularly with trivalent metal ions like gadolinium (Gd) or lutetium (Lu). It forms stable complexes with these metals, which are used in medical imaging (MRI) and radiotherapy. Sarcosine is a naturally occurring amino acid derivative which serves as a linker or spacer between DOTA and biotin, providing flexibility and accessibility to the biotin moiety.

Specifications

CAS No.180978-54-5
FormulaC36H54N8O11S·2HCl·2H2O
Molecular Weight915.9
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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