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Biotinylation Reagents

6-N-Biotinylaminohexyl Isopropyl-d7 Phosphorofluoridate, Hemihydrate | CAS 1246812-28-1

Catalog: TASK-36-1001714   CAS NO.: 1246812-28-1
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Description

6-N-Biotinylaminohexyl Isopropyl-d7 Phosphorofluoridate, Hemihydrate (6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl Phosphorofluoridic Acid 1-Methylethyl-d7 Ester Hemihydrate) integrates biotinylation with a phosphorofluoridate group, which is known for its reactivity with certain enzyme active sites, and includes a deuterium label (d7) for analytical purposes. The phosphorofluoridate group can be used to inhibit enzymes that have reactive nucleophiles in their active sites. The biotinylation allows for specific detection and quantification of enzyme activity using avidin or streptavidin-based methods. The deuterium label (d7) enables precise quantification and tracking of the compound in mass spectrometry. This helps in studying protein interactions and enzyme activity with high accuracy. The compound can help study the mechanism of action of enzymes by forming covalent bonds with active site residues. This is valuable for understanding enzyme function and inhibition.

Specifications

CAS No.1246812-28-1
FormulaC19H35FN3O5PS
Molecular Weight467.5
Purity>98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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