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Biotinylation Reagents

[Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin)-NH2

Catalog: TASK-36-1001994   CAS NO.: N/A
  • 0.5mg

$68.25$68.25

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Description

[Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin)-NH2 refers to a modified histone H3 fragment where citrullination (Cit) occurs at either arginine 2, arginine 8, or arginine 17. Histone H3 is a core histone protein that plays a crucial role in DNA packaging within the nucleus and regulates gene expression through post-translational modifications. Citrullination is a post-translational modification where arginine residues are converted to citrulline residues. This modification can affect chromatin structure and gene transcription, influencing various cellular processes and disease states. Citrullination of histones has been implicated in various diseases, including autoimmune disorders and cancer. Peptides like [Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin)-NH2 can be used to investigate how aberrant citrullination contributes to disease pathogenesis, potentially identifying new therapeutic targets or diagnostic biomarkers.

Specifications

CAS No.N/A
FormulaN/A
Molecular Weight2725.3
Purity>98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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