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Click Chemistry

PLGA-Phis-PEG-N3 (Poly(lactic-co-glycolic acid)-block-poly(L-histidine)-block-poly(ethylene glycol)-azide)

Catalog: TASK-20-5001093   CAS NO.: N/A
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Description

PLGA-Phis-PEG-N3 (Poly(lactic-co-glycolic acid)-block-poly(L-histidine)-block-poly(ethylene glycol)-azide) is a multifunctional polymer that combines the properties of poly(lactic-co-glycolic acid) (PLGA), poly(histidine) (Phis), polyethylene glycol (PEG), and an azide group (-N3). PLGA is a biodegradable and biocompatible polymer commonly used in drug delivery systems due to its ability to degrade into lactic and glycolic acid, which are naturally metabolized by the body. Poly(histidine), a pH-sensitive polymer that can respond to changes in the environment, such as pH shifts, by changing its conformation or solubility. This property is useful for drug delivery systems that release their payload in response to specific biological conditions. PLGA-Phis-PEG-N₃ is ideal for developing drug delivery systems that release their payload in response to acidic environments. The Phis segment becomes protonated and swells or degrades in acidic conditions (such as those found in tumors or inflamed tissues), triggering the release of encapsulated drugs. This property allows for targeted drug release, reducing side effects and enhancing therapeutic efficacy.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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