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APN-PEG4-PFP

Catalog: TASK-20-5002089   CAS NO.: N/A
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Description

APN-PEG4-PFP is a versatile tool for conjugating proteins, peptides, or other biomolecules. The PFP ester reacts with amines, forming a stable amide bond. This is particularly useful for modifying proteins at lysine residues or N-terminal amines. The APN moiety can provide additional functionalization by reacting with nucleophiles, allowing for dual modification or the creation of multifunctional bioconjugates. Additionally, the APN moiety can act as an electrophilic warhead for covalent attachment to nucleophiles in biological systems. This can be used for targeted enzyme inhibition or protein modification, especially in disease contexts such as cancer, where APN can react with overexpressed enzymes or proteins in the tumor microenvironment. When combined with the amine-reactive PFP ester, the molecule offers dual functionality, allowing for precise modifications in both chemical and biological contexts.

Specifications

CAS No.N/A
FormulaC27H25F5N2O7
Molecular Weight584.49
Purity98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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