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Polymers & Copolymers

RGDyC peptide-Modified PAMAM Dendrimer Conjugates Labeled with Radionuclide131I

Catalog: TASK-8-4000117   CAS NO.: N/A
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Description

RGDyC peptide-Modified PAMAM Dendrimer Conjugates Labeled with Radionuclide131I can be used in research to evaluate integrin expression profiles in various tumor types, aiding in the identification of potential targets for therapy and informing clinical decision-making. In addition, the 131I label allows for Single Photon Emission Computed Tomography (SPECT) imaging, providing real-time visualization of tumor localization and distribution of the conjugate in the body. This imaging capability is essential for treatment planning and monitoring therapeutic response. RGDyC is a synthetic peptide that consists of the amino acids arginine (R), glycine (G), aspartic acid (D), and tyrosine (yC). This sequence binds specifically to integrins (especially αvβ3), which are frequently upregulated in tumor cells and angiogenic blood vessels. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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