Polyamidoamine-Remdesivir Conjugate (PAMAM-RDV)

Catalog: TASK-8-4000164

CAS NO.: N/A

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Description

Polyamidoamine-Remdesivir Conjugate (PAMAM-RDV) refers to a chemical conjugate formed between Polyamidoamine (PAMAM) dendrimers and the antiviral drug Remdesivir. Remdesivir is originally developed for treating Ebola virus, and it has gained prominence for its role in COVID-19 treatment. It works by inhibiting the RNA-dependent RNA polymerase (RdRp) enzyme, preventing viral replication. Remdesivir’s poor bioavailability when administered alone can be addressed by the dendrimer conjugate, which can improve drug solubility and stability, ensuring more effective systemic delivery. By modifying the surface of PAMAM dendrimers, the conjugate can be engineered for targeted delivery to specific organs or tissues, such as lungs or liver, potentially improving the therapeutic index of Remdesivir and reducing off-target effects. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

CAS No.	N/A
Formula	N/A
Molecular Weight	N/A
Purity	98%
Ship Within	1-3 weeks
Storage Temp.	N/A
Shipping	4-25℃ for up to 3 weeks

Polyamidoamine-Remdesivir Conjugate (PAMAM-RDV)

Description

Specifications

Biotinylated Poly(amido)amine Dendrimers (PAMAM-Biotin)

FITC-PAMAM-RDV (Polyamidoamine-Remdesivir conjugated Fluorescein Isothiocyanate)