Biotinylated Poly(amido)amine Dendrimers (PAMAM-Biotin)

Catalog: TASK-8-4000166

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Description

Biotinylated Poly(amido)amine Dendrimers (PAMAM-Biotin) combine the well-established properties of PAMAM dendrimers (e.g., high functionality, precise molecular architecture, and branched structure) with the specific affinity of biotin for avidin or streptavidin. PAMAM-Biotin dendrimers can serve as gene delivery vehicles by attaching biotinylated nucleic acids (DNA or RNA) to their surface. Once biotinylated, these conjugates can bind to avidin-functionalized liposomes or target cells for precise gene delivery. They can also be engineered to encapsulate small molecule drugs, nucleic acids, or biologics for controlled release applications. The avidin-biotin interaction could provide a mechanism for triggering release at the desired location or upon exposure to specific stimuli (e.g., changes in pH, temperature, or enzyme activity). PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

CAS No.	N/A
Formula	N/A
Molecular Weight	N/A
Purity	98%
Ship Within	1-3 weeks
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Shipping	4-25℃ for up to 3 weeks

Biotinylated Poly(amido)amine Dendrimers (PAMAM-Biotin)

Description

Specifications