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Liposomes

DOTAP-based Fluoroliposome Containing Encapsulated Dextran-Fluorescein, Lyophilized Powder

Catalog: TASK-25-6000564   CAS NO.: N/A
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Description

DOTAP-based Fluoroliposome Containing Encapsulated Dextran-Fluorescein, Lyophilized Powder is effective for drug delivery, gene therapy, and fluorescence-based tracking studies. DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, meaning it carries a positive charge, which plays a critical role in liposome formation, cellular interaction, and cargo delivery. Dextran is a polysaccharide composed of glucose units linked by alpha-1,6-glycosidic bonds. It is a highly biocompatible, water-soluble polymer. Dextran is often used in liposomal formulations because it provides a neutral, hydrophilic environment that can encapsulate a wide range of water-soluble therapeutic agents, proteins, or dyes. The attachment of fluorescein to dextran enables real-time fluorescence imaging of liposome behavior in biological systems. This provides insight into cellular uptake, intracellular trafficking, and release kinetics of the encapsulated cargo.

Specifications

CAS No.N/A
Lipid Composition1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)/1,2-dioleoyl-sn-glycero-3-phosphocholine/Cholesterol (5/65/30)
FormLyophilized Powder
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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