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Liposomes

Plain Liposomes made from Anionic DOPC:Chol:DOPG:DOPE-PEG(2000), Lyophilized Powder (Size: 50nm/100nm/200nm/1-2μm)

Catalog: TASK-25-6000706   CAS NO.: N/A
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Description

Plain Liposomes made from Anionic DOPC:Chol:DOPG:DOPE-PEG(2000), Lyophilized Powder are advanced lipid nanoparticles with a negatively charged surface. This composition provides flexibility, biocompatibility, and extended systemic circulation, making them ideal for applications in drug delivery, diagnostics, and fundamental research. DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine) serves as the primary lipid component, contributing to the bilayer’s fluidity due to its unsaturated hydrocarbon chains. This fluid nature enhances liposomal flexibility, facilitating drug release in targeted environments. The anionic lipid DOPG (1,2-dioleoyl-sn-glycero-3-phosphoglycerol) imparts a net negative charge to the liposomes, facilitating interactions with positively charged molecules such as proteins, peptides, or drugs. DOPE conjugated with polyethylene glycol (PEG) ensures steric stabilization and immune evasion. The PEG layer minimizes opsonization, prolonging circulation time and improving the liposomes’ ability to accumulate at target sites through passive targeting mechanisms like the enhanced permeability and retention (EPR) effect.

Specifications

CAS No.N/A
Lipid CompositionDOPC:Chol:DOPG:DOPE-PEG(2000) (60:30:5:5)
FormLyophilized Powder
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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