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ADC Linkers

Alloc-Val-Ala-OH

Catalog: TASK-21-1000109   CAS NO.: 330970-70-2
  • 250mg
  • 500mg
  • 1g

$68.25$68.25

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Description

Alloc-Val-Ala-OH is a peptide linker with a terminal carboxylic acid group and an Alloc protecting group. The peptide chain can act as a cleavable linker in drug design. The Alloc group is stable to treatment with piperidine and TFA, and can be removed in neutral conditions with catalytic amounts of Pd(PPh3)4 in the presence of PhSiH3. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Specifications

CAS No.330970-70-2
FormulaC12H20N2O5
Molecular Weight272.3
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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