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Polymers & Copolymers

177Lu-labeled carboxyl-terminated polyamidoamine (PAMAM) dendrimer-RGD peptide conjugate

Catalog: TASK-8-4000112   CAS NO.: N/A
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Description

177Lu-labeled carboxyl-terminated polyamidoamine (PAMAM) dendrimer-RGD peptide conjugate refers to a significant advancement in targeted cancer therapy and imaging. By leveraging the unique properties of dendrimers, the targeting capability of RGD peptides, and the therapeutic potential of 177Lu, this conjugate has the potential to enhance the efficacy and specificity of cancer treatments. RGD (arginine-glycine-aspartic acid) is a well-known peptide that specifically binds to integrins (such as αvβ3) that are overexpressed on many tumor cells and angiogenic blood vessels. Lutetium-177 is a beta-emitting radioisotope used for targeted radiotherapy. Its emission profile makes it suitable for both therapeutic and diagnostic applications. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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