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Lipid PEGs

DOPE-PEG-Azide, DOPE-PEG-N3, MW 1,000

Catalog: TASK-02-1000024   CAS NO.: N/A
  • 100mg
  • 500mg
  • 1g

$68.25$68.25

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Description

1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DOPE)-polyethylene glycol-azide (DOPE-PEG-azide, DOPE-PEG-N3), a linear heterobifunctional PEGylation reagent with an unsaturated DOPE and azide group, is used in the preparation of pegylated liposome using Click Chemistry. Reacting readily with alkyne or cycloocytne in aqueous solution with or without copper catalyst, azide is useful for the preparation of grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. DOPE-PEG-azide is commonly used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein and peptide.

Specifications

CAS No.N/A
FormulaN/A
Molecular Weight1,000
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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