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Lipid PEGs

DSPE-PEG-COOH, DSPE-PEG-Acid, MW 2,000

Catalog: TASK-02-2000025   CAS NO.: 1403744-37-5
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Description

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine-PEG-succinic acid (DSPE-PEG-COOH, DSPE-PEG-Acid, N-succinyl-L-α-phosphatidylethanolamine, Distearoyl) is a reactive phospholipid PEG conjugates that can react with primary amine groups. DSPE is an 18 carbon phospholipid that is highly hydrophobic. PEG linker offers good hydrophilicity and water solubility. Carboxylic group (-COOH) on the other PEG terminal reacts with primary amine groups using EDC chemistry. DSPE-PEG thus can be easily incorporated into liposome and other nanoparticles via the reaction of carboxylic acid and amine. DSPE-PEG-COOH is a commonly used reactive phospholipid to conjugate antibodies, proteins, peptides or other substrates to the surface of liposome and other lipid PEG nanoparticles. PEGylated phospholipids have longer blood circulation time and higher stability for encapsulated molecules.

Specifications

CAS No.1403744-37-5
Formula(C2H4O)nC45H86NO12P.Na
Molecular Weight2,000
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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