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Lipid PEGs

DSPE-PEG-OPSS, MW 1,000

Catalog: TASK-02-2000061   CAS NO.: N/A
  • 100mg
  • 500mg
  • 1g

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Description

1,2-Distearoyl-sn-glycero-3-phosphoethanolamine (DSPE)-poly(ethylene glycol) with conjugated orthopyridyl disulfide (OPSS or PDP) (DSPE-PEG-OPSS) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a orthopyridyl disulfide. DSPE-PEG-OPSS is an 18 carbon phospholipid PEG conjugate which has both hydrophilicity and hydrophobility, which is a useful self-assembling reagent to prepare PEGylated liposome or micelle while also providing a thiol or cysteine reactive maleimide group. Orthopyridyl disulfide or pyridyldithio functional group can selectively reacts with free thiol, SH, sulfhydryl or mercapto to form a oxidation, reduction reversible disulfide bond. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs.

Specifications

CAS No.N/A
FormulaN/A
Molecular Weight1,000
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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