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Polymers & Copolymers

EGFR-targeted PAMAM-based dendrimer

Catalog: TASK-8-4000118   CAS NO.: N/A
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Description

EGFR-targeted PAMAM-based dendrimer (Epidermal growth factor receptor-targeted poly(amidoamine)-based dendrimer) is a versatile and effective platform for enhancing cancer treatment and diagnostics. EGFR-targeted PAMAM dendrimers can deliver chemotherapeutics directly to tumor cells, enhancing drug accumulation in cancer tissues while sparing healthy cells. This selectivity reduces systemic toxicity and improves the therapeutic index of the drugs. These dendrimers can also be designed to deliver multiple therapeutic agents simultaneously, such as chemotherapeutics along with targeted therapies (e.g., monoclonal antibodies). This synergistic approach can enhance treatment efficacy. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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