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ADC Linkers

FAM-Amido Hexamethylene Carbamate-PAB-Cit-Val-Alkyne

Catalog: TASK-21-1000059   CAS NO.: N/A
  • 10mg
  • 25mg

$68.25$68.25

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Description

FAM-Amido Hexamethylene Carbamate-PAB-Cit-Val-Alkyne is a cleavable ADC linker with fluorescein that undergoes enzymatic transamination. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The Val-Cit linker was designed to be cleaved by cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.

Specifications

CAS No.N/A
FormulaC52H59N7O12
Molecular Weight974.1
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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