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Liposomes

Liposomal Clodronate, Lyophilized Powder

Catalog: TASK-25-6000130   CAS NO.: N/A
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Description

Liposomal Clodronate, Lyophilized Powder is a liposome-encapsulated formulation of clodronate, a bisphosphonate that is used primarily to deplete macrophages and monocytes in vivo. The liposomal formulation of clodronate enhances its ability to selectively target and accumulate in phagocytic cells like macrophages and monocytes, which play critical roles in inflammation, immunity, and tissue homeostasis. Clodronate is a bisphosphonate that inhibits osteoclast activity, which is important in the treatment of bone resorption diseases like osteoporosis. However, when used in liposomal form, its main application is as an agent to deplete macrophages and monocytes. Overall, Liposomal Clodronate is an effective tool for macrophage and monocyte depletion in vivo, enabling researchers to study the critical roles these cells play in various diseases, including cancer, autoimmune conditions, inflammation, and infections.

Specifications

CAS No.N/A
Lipid CompositionL-alpha-Phosphatidylcholine/Cholesterol (ratio: 70/30)
FormLyophilized Powder
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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