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MC-Val-Cit-PAB-MMAE

Catalog: TASK-21-1000061   CAS NO.: 646502-53-6
  • 10mg
  • 20mg

$68.25$68.25

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Description

MC-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate which contains a thio reactive maleimidocaproyl (MC) group, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. It acts as a potent mitotic inhibitor by inhibiting tubulin polymerization. Valine-citrulline is a common lysosomal cleavable dipeptide. PAB is a typical self-immolation spacer.

Specifications

CAS No.646502-53-6
FormulaC68H105N11O15
Molecular Weight1316.7
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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