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Click Chemistry

N3-PEG-D-Mannose (Azido-PEG-D-Mannose)

Catalog: TASK-20-5001862   CAS NO.: N/A
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Description

N3-PEG-D-Mannose (Azido-PEG-D-Mannose) merges the natural properties of mannose, which plays an essential role in cell signaling and glycoprotein interactions, with the solubility and flexibility of PEG, and the reactivity of the azido group for bioorthogonal click chemistry. D-mannose has a high affinity for mannose receptors (e.g., CD206), which are overexpressed on the surface of immune cells like macrophages and dendritic cells. By conjugating therapeutic agents to N3-PEG-D-mannose, these drugs can be specifically targeted to immune cells, potentially improving drug delivery for immune-related conditions such as inflammation, infections, or cancer. The PEG linker increases the solubility of the mannose-drug conjugate in biological systems, enhances circulation time, and minimizes immune detection. This reduces the degradation of the drug and allows for sustained release at the target site.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1 week
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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