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ADC Linkers

NHS ester-PEG4-Val-Cit-PAB-MMAE

Catalog: TASK-21-2000036   CAS NO.: 2762518-86-3
  • 10mg
  • 20mg

$68.25$68.25

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Description

NHS ester-PEG4-Val-Cit-PAB-MMAE is a compound designed for targeted drug delivery, particularly in cancer therapy. The NHS ester allows for the specific conjugation of the molecule to amine-containing biomolecules, such as antibodies or peptides, through stable amide bond formation. The PEG4 linker provides flexibility and solubility to the molecule while minimizing steric hindrance. The Val-Cit dipeptide and PAB linker confer stability and specificity to the conjugate, allowing for controlled release of MMAE inside target cells through cleavage of the PAB linker by intracellular enzymes.

Specifications

CAS No.2762518-86-3
FormulaC74H117N11O21
Molecular Weight1496.8
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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