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Polymers & Copolymers

PADRE-conjugated PAMAM Dendrimer (PPD)

Catalog: TASK-8-4000109   CAS NO.: N/A
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Description

PADRE-conjugated PAMAM Dendrimer (PPD) is an innovative approach in immunotherapy and drug delivery. PADRE is a synthetic peptide derived from the sequence of T-cell epitopes that binds to multiple HLA-DR molecules, facilitating T-cell activation. The conjugation of PADRE to PAMAM dendrimers enhances the dendrimer’s immunogenic properties, promoting robust immune responses. PADRE-conjugated PAMAM dendrimers can serve as vaccine carriers, enhancing the delivery of tumor antigens and stimulating T-cell responses against tumors. Besides, by presenting PADRE alongside therapeutic agents, these dendrimers can improve the targeted delivery of drugs to antigen-presenting cells (APCs), enhancing therapeutic efficacy. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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