PAMAM dendrimer complexed to 7-ethyl-10-hydroxy-camptothecin

Catalog: TASK-8-4000098

CAS NO.: N/A

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Description

PAMAM dendrimer complexed to 7-ethyl-10-hydroxy-camptothecin refers to a nanocarrier system designed to deliver SN-38, an active metabolite of the chemotherapeutic agent irinotecan. SN-38 is a potent topoisomerase I inhibitor, which interferes with DNA replication and transcription. PAMAM-SN-38 complexes can be utilized to deliver SN-38 directly to tumor cells, enhancing its anticancer effects and minimizing systemic toxicity. Additionally, PAMAM dendrimers can be modified to include imaging agents alongside SN-38, allowing for simultaneous therapy and monitoring of treatment response using imaging techniques. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

CAS No.	N/A
Formula	N/A
Molecular Weight	N/A
Purity	98%
Ship Within	1-3 weeks
Storage Temp.	N/A
Shipping	4-25℃ for up to 3 weeks

PAMAM dendrimer complexed to 7-ethyl-10-hydroxy-camptothecin

Description

Specifications

PAMAM-G1 dendrimers containing neutral (-OH-90%) and cationic (-NH2-10%)

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PAMAM-Poly(ethylene glycol)-Glutathione (PAMAM-PEG-GSH)

PAMAM-G4 conjugated to glutathione (PAMAM-GSH)

PAMAM-Arginine-glycine-aspartic acid-Poly(ethylene glycol) (PAMAM-RGD-PEG)

PAMAM-Polyvalerolactone-Poly(ethylene glycol) (PAMAM-PVL-PEG)

PAMAM dendrimer conjugated to CNDs (carbon nanodots)