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Polymers & Copolymers

PEG-conjugated PAMAM dendrimer

Catalog: TASK-8-4000115   CAS NO.: N/A
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Description

PEG-conjugated PAMAM (Polyamidoamine) dendrimers are engineered nanocarriers that combine the unique structural properties of PAMAM dendrimers with the biocompatibility and solubility-enhancing characteristics of polyethylene glycol (PEG). PEG-conjugated PAMAM dendrimers can effectively encapsulate plasmid DNA, siRNA, or mRNA, protecting them from degradation in biological environments. The cationic nature of PAMAM dendrimers facilitates the formation of stable complexes with negatively charged nucleic acids, enabling their transport into cells. Moreover, these conjugates are especially relevant in gene therapy, where delivering therapeutic genes or RNAi molecules directly to target cells can correct genetic disorders or inhibit the expression of harmful genes. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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