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Liposomes

Plain Unsaturated 16:1 (Δ9-Cis) PC: Cholesterol Liposomes, Lyophilized Powder (Size: 50nm/100nm/200nm/1-2μm)

Catalog: TASK-25-6000733   CAS NO.: N/A
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Description

Plain Unsaturated 16:1 (Δ9-Cis) PC: Cholesterol Liposomes, Lyophilized Powder are primarily determined by the interaction between phospholipids and cholesterol. The phospholipids in these liposomes consist of palmitoleic acid (16:1, Δ9-cis), a monounsaturated fatty acid, which is integrated into the phosphatidylcholine backbone. This unsaturated fatty acid introduces a cis double bond (Δ9-cis) at the 9th position of the fatty acid tail, causing a bend in the hydrocarbon chain and leading to a more fluid and flexible membrane structure. The cholesterol in the liposome formulation plays a critical role in modulating the fluidity and stability of the lipid bilayer. Cholesterol intercalates between the phospholipid molecules, reducing membrane permeability, enhancing bilayer packing, and providing structural integrity. The balance between the unsaturated 16:1 PC and cholesterol results in a lipid bilayer with controlled flexibility and stability, offering advantages in forming liposomes that are both stable in circulation and capable of undergoing structural changes when interacting with biological membranes, such as during drug release or fusion with target cells.

Specifications

CAS No.N/A
Lipid Composition16:1 (Δ9-Cis) PC: Cholesterol (70:30)
FormLyophilized Powder
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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