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Polymers & Copolymers

Polyacrylic Acid-conjugated Polyamidoamine G4.0 Dendrimer (PAA-conjugated PAMAM G4.0)

Catalog: TASK-8-4000162   CAS NO.: N/A
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Description

Polyacrylic Acid-conjugated Polyamidoamine G4.0 Dendrimer (PAA-conjugated PAMAM G4.0) is a promising nanomaterial with wide-ranging applications, particularly in drug delivery, gene therapy, and nanomedicine. The polyacrylic acid component provides pH-sensitive characteristics, which are ideal for controlled drug release. At acidic pH (such as in the lysosome or tumors), PAA can undergo conformational changes, enhancing the release of the drug payload. PAMAM dendrimers are well-known gene delivery vehicles. When conjugated with polyacrylic acid, the conjugate can encapsulate genetic material such as DNA or RNA. The PAA provides additional stability, while the dendrimer’s multiple amine groups facilitate electrostatic interactions with the negatively charged nucleic acids, promoting efficient gene delivery. PAMAM dendrimers are commonly utilized in pharmaceuticals for targeted drug delivery and gene therapy, in diagnostics as biosensors and imaging agents, in cosmetics for active ingredient delivery, and in materials science for enhancing properties in nanocomposites and catalysts. Taskcm can provide PAMAM dendrimers in kilograms.

Specifications

CAS No.N/A
FormulaN/A
Molecular WeightN/A
Purity98%
Ship Within1-3 weeks
Storage Temp.N/A
Shipping4-25℃ for up to 3 weeks
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