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Val-Cit-PAB-MMAE

Catalog: TASK-21-1000060   CAS NO.: 644981-35-1
  • 5mg
  • 10mg

$68.25$68.25

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Description

Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate which contains a protease-sensitive Val-Cit dipeptide, and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. It acts as a potent mitotic inhibitor by inhibiting tubulin polymerization. Valine-citrulline is a common lysosomal cleavable dipeptide. PAB is a typical self-immolation spacer.

Specifications

CAS No.644981-35-1
FormulaC58H94N10O12
Molecular Weight1123.5
Purity98%
Ship Within1 week
Storage Temp.-20℃
Shipping4-25℃ for up to 3 weeks
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